Effects of peer social interaction on performance during computerized cognitive remediation therapy in patients with early course schizophrenia: A pilot study

SCHIZOPHRENIA RESEARCH

卷:203

Article

Sandoval, Luis R.¹  Gonzalez, Betzamel Lopez¹  Stone, William S.¹  Guimond, Synthia¹  Torres Rivas, Cristina^2,3  Sheynberg, David¹  Kuo, Susan S.⁴  Eack, Shaun⁴  Keshavan, Matcheri S.¹ 

[1] Harvard Med Sch, Dept Psychiat, Beth Israel Deaconess Med Ctr, 330 Brookline Ave, Boston, MA 02115 USA

[2] Consorci Sanitari Maresme, Mataro, Spain

[3] Univ Ramon Llull, FPCEE Blanquerna, Barcelona, Spain

[4] Univ Pittsburgh, Pittsburgh, PA 15260 USA

关键词: Cognitive remediation;    Schizophrenia;    Mental health;    Social interaction;    Psychosis;    Computerized interventions;   

DOI  :  10.1016/j.schres.2017.08.049

来源: Elsevier

【 摘 要 】

Background: Recent studies show that computer-based training enhances cognition in schizophrenia; furthermore, socialization has also been found to improve cognitive functions. It is generally believed that non-social cognitive remediation using computer exercises would be a pre-requisite for therapeutic benefits from social cognitive training. However, it is also possible that social interaction by itself enhances non-social cognitive functions; this possibility has scarcely been explored in schizophrenia patients. This pilot study examined the effects of computer-based neurocognitive training, along with social interaction either with a peer (PSI) or without one (N-PSI). We hypothesized that PSI will enhance cognitive performance during computerized exercises in schizophrenia, as compared with N-PSI. Methods: Sixteen adult participants diagnosed with schizophrenia or schizoaffective disorder participating in an ongoing trial of Cognitive Enhancement Therapy completed several computerized neurocognitive remediation training sessions (the Orientation Remedial Module (c), or ORM), either with a peer or without a peer. Results: We observed a significant interaction between the effect of PSI and performance on the different cognitive exercises (p < 0.05). More precisely, when patients performed the session with PSI, they demonstrated better cognitive performances than with N-PSI in the ORM exercise that provides training in processing speed, alertness, and reaction time (the standard Attention Reaction Conditioner, or ARC) (p < 0.01, corrected). PSI did not significantly affect other cognitive domains such as target detection and spatial attention. Conclusion: Our findings suggest that PSI could improve cognitive performance, such as processing speed, during computerized cognitive training in schizophrenia. Additional studies investigating the effect of PSI during cognitive remediation are needed to further evaluate this hypothesis. (C) 2017 Published by Elsevier B.V.

【 授权许可】

Free