Light-controlled, living radical polymerisation mediated by fluorophore-conjugated RAFT agents

POLYMER

卷:226

Article

Zhang, Shuo¹  Zhang, Yichuan^1,2  Ucuncu, Muhammed^1,3  Lilienkampf, Annamaria¹  Geng, Jin²  Bradley, Mark¹ 

[1] Univ Edinburgh, EaStCHEM Sch Chem, Joseph Black Bldg, Edinburgh, Midlothian, Scotland

[2] Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen, Peoples R China

[3] Izmir Katip Celebi Univ, Fac Pharm, Dept Analyt Chem, Izmir, Turkey

关键词: BODIPY;    Carboxyfluorescein;    Photoinduced electron transfer-reversible;    addition-fragmentation chain-transfer (PET-RAFT) polymerisation;   

DOI  :  10.1016/j.polymer.2021.123840

来源: Elsevier

【 摘 要 】

Photoinduced electron transfer-reversible addition-fragmentation chain-transfer (PET-RAFT) polymerisation allows the controlled synthesis of polymers and provides an alternative to transition metal-based photoinitiators. Here, fluorophore-conjugated RAFT agents, containing either 5-carboxyfluorescein or a boron-dipyrromethene (BODIPY) moiety attached to a thiocarbonylthio group, were synthesised. Both agents enabled light-controlled (470 nm, 0.4 mW/cm2) on/off polymerisation yielding polymers with a Mw/Mn < 1.50. The BODIPY-based RAFT agent showed excellent photostability and gave polymers that contained a single fluorophore per polymer chain, providing an expedient route to homogeneous fluorescently labelled polymers. This agent was compatible with multiple acrylamide/acrylate monomers with a range of functional groups, with the thiocarbonylthio terminating group enabling further polymer chain extension and the formation of fluorescent block copolymers, as demonstrated by the synthesis of BODIPY-labelled poly(N,N-dimethylacrylamide)-block-poly (3acrylamidophenyl)boronic acid).

【 授权许可】

Free