Age-related differences in neural spectral power during motor learning

NEUROBIOLOGY OF AGING

卷:77

Article

Rueda-Delgado, Laura Milena¹  Heise, Kirstin Friederike¹  Daffertshofer, Andreas²  Mantini, Dante^1,3  Swinnen, Stephan Patrick^1,4 

[1] Katholieke Univ Leuven, Dept Movement Sci, Movement Control & Neuroplastic Res Grp, Tervuurse Vest 101, B-3001 Leuven, Belgium

[2] Vrije Univ Amsterdam, Dept Human Movement Sci, Fac Behav & Movement Sci, Amsterdam Movement Sci & Inst Brain & Behav, Amsterdam, Netherlands

[3] IRCCS San Camillo Hosp Fdn, Funct Neuroimaging Lab, Venice, Italy

[4] Katholieke Univ Leuven, LBI, Leuven, Belgium

关键词: Motor learning;    Aging;    Spectral analysis;    Electroencephalography;    Linear mixed-effects model;   

DOI  :  10.1016/j.neurobiolaging.2018.12.013

来源: Elsevier

【 摘 要 】

We investigated how older adults preserve the capability to acquire new motor skills in the face of age-related brain alterations. We assessed neural changes associated with learning a bimanual coordination task over 4 days of practice in healthy young (n = 24) and older adults (n = 24). The electroencephalogram was recorded during task performance at the start and end of training. Motor performance improved with practice in both groups, but the amount of learning was lower in the older adults. Beta power (15-30 Hz) in sensorimotor and prefrontal cortices of older adults was reduced with training, indicative of higher neural activity. We also found a functional reorganization after training in beta and alpha (8-12 Hz) bands. Between-session changes in alpha and beta power differed between groups in several cortical areas: young adults exhibited reduced power in the beta band in sensorimotor cortices, whereas older adults displayed a smaller decrease. Our findings indicate a less flexible reorganization of neural activity accompanying learning in older adults compared with young adults. (C) 2019 Elsevier Inc. All rights reserved.

【 授权许可】

Free