No clinical relevance of the height of fundal indentation in subseptate or arcuate uterus: a prospective study

REPRODUCTIVE BIOMEDICINE ONLINE

卷:24

Article

Gergolet, Marco¹  Campo, Rudi²  Verdenik, Ivan³  Suster, Natasa Kenda³  Gordts, Stephan²  Gianaroli, Luca⁴ 

[1] SIFES Doo, Reprod Surg, Nova Gorica 5000, Slovenia

[2] LIFE, B-3000 Louvain, Belgium

[3] Univ Ljubljana, Dept Obstet & Gynaecol, Ljubljana 1000, Slovenia

[4] SISMER, Reprod Med Unit, I-40138 Bologna, Italy

关键词: arcuate uterus;    congenital uterine anomalies classification;    septate uterus;    subseptate uterus;    spontaneous miscarriage;    hysteroscopic metroplasty;   

DOI  :  10.1016/j.rbmo.2012.01.025

来源: Elsevier

【 摘 要 】

The American Fertility Society has classified the arcuate uterus as a minor malformation with a benign clinical behaviour. The aim of this prospective study was to verify whether there is any scientific basis for this differentiation. Patients with at least one early miscarriage and a subseptate or arcuate uterus were admitted for hysteroscopic metroplasty. Patients were allocated to a subseptate uterus group, with an indentation of 1.5 cm or more, or an arcuate uterus group, with a smaller indentation. The miscarriage rates after metroplasty were similar between the two groups (14.0% in the subseptate uterus group versus 11.1% in the arcuate uterus group). Before metroplasty, the miscarriage rates were significantly higher in subseptate uterus group, as well as in the arcuate uterus group (both P < 0.001). According to these results, there is no evidence to support that the arcuate uterus has a different effect on the reproductive outcome in comparison to the subseptate uterus, neither before nor after surgical correction of the anomaly. Since there is no scientific basis for a separate classification of the arcuate uterus, a review of the classifications of uterine congenital anomalies should be considered as necessary. (C) 2012, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

Free