Meditation and mindfulness reduce perceived stress in women with recurrent pregnancy loss: a randomized controlled trial

REPRODUCTIVE BIOMEDICINE ONLINE

卷:43

Article

Jensen, Karen Henriette Kirchheiner^1,2  Krog, Maria Christine^1,2,5  Koert, Emily³  Hedegaard, Signe^1,2  Chonovitsch, Marie^1,2  Schmidt, Lone³  Kolte, Astrid Marie^1,2,4  Nielsen, Henriette Svarre^1,2,4 

[1] Copenhagen Univ Hosp, Rigshosp, Fertil Clin, Recurrent Pregnancy Loss Unit, DK-4071 Copenhagen O, Denmark

[2] Hvidovre Univ Hosp, Dept Obstet & Gynaecol, Hvidovre, Denmark

[3] Univ Copenhagen, Sect Social Med, Dept Publ Hlth, Copenhagen O, Denmark

[4] Univ Copenhagen, Dept Clin Med, Copenhagen N, Denmark

[5] Copenhagen Univ Hosp, Rigshosp, Dept Clin Immunol, Copenhagen O, Denmark

关键词: Education;    Meditation;    Randomized controlled trial;    Recurrent pregnancy loss;    Stress;   

DOI  :  10.1016/j.rbmo.2021.04.018

来源: Elsevier

【 摘 要 】

Research question: Can participating in a tailored 7-week meditation and mindfulness programme with additional standard supportive care versus standard supportive care only reduce perceived stress for women with recurrent pregnancy loss (RPL)? Design: A two-armed randomized controlled trial (RCT) with 12-month follow-up. In total 76 patients were enrolled and randomly assigned to either standard supportive care or to a 7-week meditation and mindfulness programme led by an instructor in addition to standard supportive care. Results: At intervention completion (after 7 weeks), perceived stress decreased significantly both in the intervention group (P = 0.001) and in the control group (P = 0.006). The decrease in perceived stress in the intervention group was significantly larger (P = 0.027) compared with the control group. At the 12-month follow-up perceived stress was still significantly decreased in both groups compared with baseline (P < 0.0001 in the intervention group and P = 0.002 in the control group). Conclusion: This first RCT of a tailored meditation and mindfulness intervention for women with RPL documents that a 7-week daily at-home meditation and mindfulness programme combined with group sessions reduced perceived stress significantly more than a standard supportive care programme. Future studies should address the most effective format and the 'dose' needed for an impact on perceived stress levels.

【 授权许可】

Free