Trauma exposure and PTSD in women with schizophrenia and coexisting substance use disorders: Comparisons to women with severe depression and substance use disorders

PSYCHIATRY RESEARCH

卷:220

Article

Aakre, Jennifer M.¹  Brown, Clayton H.^1,2  Benson, Kathleen M.³  Drapalski, Amy L.¹  Gearon, Jean S.⁴ 

[1] VA Maryland Healthcare Syst, Mental Illness Res Educ & Clin Ctr MIRECC, VA Capitol Healthcare Network VISN 5, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA

[3] Louis Stokes Cleveland VA Med Ctr, Cleveland, OH 44106 USA

[4] George Washington Univ, Sch Med & Hlth Sci, Dept Psychiat & Behav Sci, Washington, DC 20037 USA

关键词: Serious mental illness;    Posttraumatic stress disorder;    Substance abuse;   

DOI  :  10.1016/j.psychres.2014.10.004

来源: Elsevier

【 摘 要 】

The present study compared rates of trauma exposure and PTSD among three groups of women at high trauma risk: those with substance use disorders (SUD) and schizophrenia (n=42), those with SUD and severe, nonpsychotic depression (n=38), and those with SUD and no other DSM-IV Axis I condition (n=37). We hypothesized that exposure to traumatic stressors and current diagnosis of PTSD would be more common in women with schizophrenia and SUD, when compared to the other two groups. Results indicate that women with schizophrenia and SUD had a more extensive trauma history than women with SUD only, and were also more likely to have PTSD. Women with schizophrenia had a fourfold greater likelihood of meeting criteria for current PTSD than were women with severe, nonpsychotic depression when potential confounds of age, race, education, severity of trauma history, and childhood trauma exposure were controlled. These results lend support to the possibility that women with psychosis have an elevated vulnerability to PTSD symptomology when exposed to life stressors that is distinct from the vulnerability associated with coexisting nonpsychotic SMI. The psychological sequelae of trauma are substantial and should be addressed in women seeking treatment for schizophrenia and problematic substance use. Published by Elsevier Ireland Ltd.

【 授权许可】

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