Delusions in first-episode psychosis: Principal component analysis of twelve types of delusions and demographic and clinical correlates of resulting domains

PSYCHIATRY RESEARCH

卷:243

Article

Paolini, Enrico^1,2  Moretti, Patrizia³  Compton, Michael T.^2,4 

[1] Univ Perugia, Sch Psychiat, Perugia, PG, Italy

[2] Lenox Hill Hosp, Dept Psychiat, New York, NY 10021 USA

[3] Univ Perugia, Dept Med, Div Psychiat Clin Psychol & Psychiat Rehabil, Perugia, PG, Italy

[4] Hofstra Northwell Sch Med, Dept Psychiat, Hempstead, NY USA

关键词: Childhood adversities;    Delusions;    Depression;    Drugs of abuse;    Hallucinations;    Paranoia;    Persecutory delusions;   

DOI  :  10.1016/j.psychres.2016.06.002

来源: Elsevier

【 摘 要 】

Although delusions represent one of the core symptoms of psychotic disorders, it is remarkable that few studies have investigated distinct delusional themes. We analyzed data from a large sample of first-episode psychosis patients (n=245) to understand relations between delusion types and demographic and clinical correlates. First, we conducted a principal component analysis (PCA) of the 12 delusion items within the Scale for the Assessment of Positive Symptoms (SAPS). Then, using the domains derived via PCA, we tested a priori hypotheses and answered exploratory research questions related to delusional content. PCA revealed five distinct components: Delusions of Influence, Grandiose/Religious Delusions, Paranoid Delusions, Negative Affect Delusions (jealousy, and sin or guilt), and Somatic Delusions. The most prevalent type of delusion was Paranoid Delusions, and such delusions were more common at older ages at onset of psychosis. The level of Delusions of Influence was correlated with the severity of hallucinations and negative symptoms. We ascertained a general relationship between different childhood adversities and delusional themes, and a specific relationship between Somatic Delusions and childhood neglect. Moreover, we found higher scores on Delusions of Influence and Negative Affect Delusions among cannabis and stimulant users. Our results support considering delusions as varied experiences with varying prevalences and correlates. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free