Relationship between whole blood serotonin and repetitive behaviors in autism

PSYCHIATRY RESEARCH

卷:175

Article

Kolevzon, Alexander^1,2  Newcorn, Jeffrey H.¹  Kryzak, Lauren²  Chaplin, William³  Watner, Dryden³  Hollander, Eric^1,2,6  Smith, Christopher J.⁴  Cook, Edwin H., Jr.⁵  Silverman, Jeremy M.^1,2 

[1] Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA

[2] Mt Sinai Sch Med, Seaver Autism Ctr Res & Treatment, New York, NY 10029 USA

[3] St Johns Univ, Dept Psychol, New York, NY USA

[4] SW Autism Res & Resource Ctr, Phoenix, AZ USA

[5] Univ Illinois, Dept Psychiat, Inst Juvenile Res, Chicago, IL 60612 USA

[6] Montefiore Med Ctr, Albert Einstein Coll Med, Dept Psychiat, Bronx, NY USA

关键词: Autism;    Serotonin;    Repetitive behavior;    Self-injury;    Aggression;   

DOI  :  10.1016/j.psychres.2009.02.008

来源: Elsevier

【 摘 要 】

This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However. a significant inverse relationship between serotonin level and self-injury was demonstrated. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free