The Test Your Memory test performs better than the MMSE in a population without known cognitive dysfunction

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:328

Article

Koekkoek, Paula S.¹  Rutten, Guy E. H. M.¹  van den Berg, Esther^2,3  van Sonsbeek, Sanne²  Gorter, Kees J.¹  Kappelle, L. Jaap²  Biessels, Geert Jan² 

[1] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands

[2] Univ Med Ctr Utrecht, Rudolf Magnus Inst Neurosci, Dept Neurol, NL-3508 GA Utrecht, Netherlands

[3] Univ Utrecht, Helmholtz Inst, Utrecht, Netherlands

关键词: Cognitive functioning;    Screening;    Test Your Memory test;    Neuropsychological test;    Mini-Mental State Examination;   

DOI  :  10.1016/j.jns.2013.02.028

来源: Elsevier

【 摘 要 】

Aim: To examine the relation of performance on the self-administered Test Your Memory test (TYM) and the Mini-Mental State Examination (MMSE) with a comprehensive neuropsychological assessment in a population sample including people with modest cognitive decrements. Methods: Eighty-six participants (aged 56-77 years), without known cognitive dysfunction, performed a neuropsychological assessment including MMSE, and were asked to fill out the TYM. The relation between both the TYM and the MMSE and a neuropsychological assessment was examined by means of correlation analyses, area under the ROC curves for discriminating between a normal and modest decrements(>= 1SD below the sample mean) group, and Bland-Altman plots. Results: Correlation with the full neuropsychological assessment was significantly stronger for the TYM than the MMSE (r = 0.78 versus r = 0.55; Steiger's Z = 2.66, p < 0.01). The TYM showed an area under the ROC-curve of 0.88 (95% CI 0.80 to 0.97) for differentiating between normal and modest decrements compared with 0.71 (0.53 to 0.90) for the MMSE. Bland-Altman plots showed limits of agreement for the TYM of -1.10 to 1.10 and for the MMSE of -1.39 to 1.38. Conclusions: The TYM showed good correlation with a neuropsychological assessment, performed better in discriminating between variations of cognition and showed more agreement with a neuropsychological assessment than the MMSE. (c) 2013 Elsevier B.V. All rights reserved.

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