A significant correlation between cauda equina conduction time and cerebrospinal fluid protein in chronic inflammatory demyelinating polyradiculoneuropathy

JOURNAL OF THE NEUROLOGICAL SCIENCES

卷:384

Article

Matsumoto, Hideyuki^1,2  Hanajima, Ritsuko³  Terao, Yasuo⁴  Hamada, Masashi²  Shirota, Yuichiro²  Yugeta, Akihiro²  Nakatani-Enomoto, Setsu⁵  Hashida, Hideji¹  Ugawa, Yoshikazu⁵ 

[1] Japanese Red Cross Med Ctr, Dept Neurol, Tokyo, Japan

[2] Univ Tokyo, Dept Neurol, Tokyo, Japan

[3] Tottori Univ, Div Neurol, Dept Brain & Neurosci, Fac Med, Tottori, Japan

[4] Univ Kyorin, Dept Cell Physiol, Mitaka, Tokyo, Japan

[5] Fukushima Med Univ, Sch Med, Dept Neurol, Fukushima, Japan

关键词: Chronic inflammatory demyelinating;    polyradiculoneuropathy (CIDP);    Magnetic stimulation;    Motor-evoked potential;    Spinal nerve;    Cauda equina;   

DOI  :  10.1016/j.jns.2017.11.006

来源: Elsevier

【 摘 要 】

We investigated the relationship between the involvement of the cauda equina in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and the increment of cerebrospinal fluid (CSF) protein. We measured cauda equina conduction time (CECT) in 14 CIDP patients using magnetic stimulation with a MATS coil. Statistical analysis revealed that CECT and CSF protein had a significant positive linear correlation. Conduction time of the peripheral nerve trunk, in contrast, had no significant linear correlation with CSF protein. We revealed that the involvement of the cauda equina and increment of CSF protein are closely related. In CIDP cases with elevated CSF protein, spinal nerves including the cauda equina are very likely involved.

【 授权许可】

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