Synthesis and evaluation of a series of C5′-substituted duocarmycin SA analogs

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

卷:20

Article

Boger, Dale L.¹ 

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

关键词: Duocarmycin SA;   

DOI  :  10.1016/j.bmcl.2010.03.078

来源: Elsevier

【 摘 要 】

The synthesis and evaluation of a key series of analogs of duocarmycin SA, bearing a single substituent at the C5' position of the DNA binding subunit, are described. (C) 2010 Elsevier Ltd. All rights reserved.

【 授权许可】

Free