期刊论文详细信息
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 卷:23 |
Novel tacrine-related drugs as potential candidates for the treatment of Alzheimer's disease | |
Article | |
Romero, Alejandro1  Cacabelos, Ramon2  Oset-Gasque, Maria J.3  Samadi, Abdelouahid4  Marco-Contelles, Jose4  | |
[1] Univ Complutense Madrid, Fac Vet Med, Dept Pharmacol & Toxicol, E-28040 Madrid, Spain | |
[2] Inst CNS Disorders & Genom Med, EuroEspes Biomed Res Ctr, Corunna 15166, Spain | |
[3] Univ Complutense Madrid, Fac Pharm, Dept Biochem & Mol Biol 2, E-28040 Madrid, Spain | |
[4] Inst Gen Organ Chem CSIC, Med Chem Lab, Madrid 28006, Spain | |
关键词: Tacrine; Cholinesterase inhibitors; Multi-target-directed ligands; New tacrine hybrids; Hepatotoxicity; Alzheimer's disease; | |
DOI : 10.1016/j.bmcl.2013.02.017 | |
来源: Elsevier | |
【 摘 要 】
A summary of the recently published efforts on tacrine derivatives as a renewed potential therapeutic approach for the treatment of Alzheimer's disease is presented. (C) 2013 Elsevier Ltd. All rights reserved.
【 授权许可】
Free
【 预 览 】
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