Cerebrovascular perfusion among older adults is moderated by strength training and gender

NEUROSCIENCE LETTERS

卷:560

Article

Xu, Xiaomeng^1,2  Jerskey, Beth A.^2,3  Cote, Denise M.³  Walsh, Edward G.⁴  Hassenstab, Jason J.^5,6  Ladino, Maura E.^3,7  Clark, Uraina S.^2,8  Labbe, Donald R.²  Gunstad, John J.⁹  Poppas, Athena¹⁰  Cohen, Ronald A.^2,11,12  Hoge, Richard D.^13,14  Sweet, Lawrence H.^2,3,15 

[1] Idaho State Univ, Dept Psychol, Pocatello, ID 83209 USA

[2] Brown Univ, Alpert Med Sch, Dept Psychiat & Human Behav, Providence, RI 02912 USA

[3] Butler Hosp, Neuroimaging Ctr, Providence, RI 02906 USA

[4] Brown Univ, Dept Neurosci, Providence, RI 02912 USA

[5] Washington Univ, St Louis Sch Med, Dept Neurol, St Louis, MO 63110 USA

[6] Washington Univ, St Louis Sch Med, Dept Psychol, St Louis, MO 63110 USA

[7] Columbia Univ, Teachers Coll, Dept Clin Psychol, New York, NY 10027 USA

[8] Icahn Sch Med Mt Sinai, Dept Neurol, New York, NY 10029 USA

[9] Kent State Univ, Dept Psychol, Kent, OH 44242 USA

[10] Brown Univ, Dept Med, Alpert Med Sch, Providence, RI 02912 USA

[11] Univ Florida, Ctr Cognit Aging & Memory, Dept Neurol, Gainesville, FL 32611 USA

[12] Univ Florida, Ctr Cognit Aging & Memory, Dept Psychiat & Aging, Gainesville, FL 32611 USA

[13] Univ Montreal, Ctr Rech, Inst Univ Geriatrie, Dept Neurosci, Montreal, PQ H3C 3J7, Canada

[14] Univ Montreal, Ctr Rech, Inst Univ Geriatrie, Dept Radiol, Montreal, PQ H3C 3J7, Canada

[15] Univ Georgia, Dept Psychol, Athens, GA 30602 USA

关键词: Cerebral perfusion;    Strength training;    Sex;    Physical activity;    ASL;   

DOI  :  10.1016/j.neulet.2013.12.011

来源: Elsevier

【 摘 要 】

Cerebral perfusion is important in older adults as it is linked to cognitive declines. Physical activity can improve blood flow in the body but little is known about the relationship between physical activity and cerebral perfusion in older adults. In particular, no study has investigated the relation between strength training and cerebral perfusion. We examined whether different types of physical activity (assessed with the Rapid Assessment of Physical Activity questionnaire) were associated with MRI cerebrovascular perfusion in 59 older adults. There was a significant interaction between gender and strength training, such that women who engaged in strength training (weight lifting or calisthenics) at least once per week exhibited significantly greater cerebrovascular perfusion than women who did not. This interaction remained significant after controlling for other physical activity, demographics, and health variables. These findings suggest that regular strength training can be beneficial for cerebrovascular health in women. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free