NEUROSCIENCE LETTERS | 卷:749 |
Neurological issues during severe COVID-19 in a tertiary level hospital in Western India | |
Article | |
Dravid, Ameet N.1  Mane, Dileep N.1  Khan, Zafer A.1  | |
[1] Noble Hosp & Res Ctr, Dept Med, Pune, Maharashtra, India | |
关键词: Neuro COVID-19; India; Cerebrovascular disease; Large vessel ischemic stroke; Encephalopathy; Myalgia; Anosmia; Dysgeusia; Poliomyelitis; COVID-19/Central nervous system tuberculosis co-infection; | |
DOI : 10.1016/j.neulet.2021.135692 | |
来源: Elsevier | |
【 摘 要 】
Background: India has the second largest COVID-19 epidemic in the world as per current estimates. Central and peripheral nervous system involvement in COVID-19 (Neuro COVID-19) has been increasingly identified and reported. This letter is the first report of the spectrum of neurological disorders observed in patients with severe COVID-19 from a resource limited setting like India. Till October 30th 2020, Noble hospital and research center, Pune, India has admitted 2631 patients of COVID-19. Out of these, 423 patients had severe COVID-19. Neurologic complications in severe COVID-19 in Pune, India: Of the 423 patients with severe COVID-19, 20 (4.7%) had pre-existing neurologic co-morbidities, with cerebrovascular disease (8 patients) being the most common. Poliomyelitis (4 patients) was also an important co-morbidity associated with severe COVID-19. Bodyache or myalgia (207/423, 49 %) and headache (59/423, 13.9 %) were the most common neurologic symptoms observed in patients. Encephalopathy (22/423, 5.2 %) and new onset large vessel ischemic stroke secondary to cerebral artery thrombosis (5/423, 1.1%) were the most common secondary neurologic complications noted in our cohort. Two cases of COVID-19/central nervous system tuberculosis co-infection were also identified. Challenges in management of Neuro COVID-19 in India: Various challenges like an overwhelmed health care system, inadequate workforce, lack of exhaustive reporting of symptoms and poor availability of neuroimaging in ventilated COVID-19 patients leads to underestimation of Neuro COVID-19 in resource limited settings like India.
【 授权许可】
Free
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
10_1016_j_neulet_2021_135692.pdf | 3152KB | download |