期刊论文详细信息
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 卷:1866
Stem Cells for Treatment of Musculoskeletal Conditions - Orthopaedic/Sports Medicine Applications
Article
Zumwalt, Mimi1  Reddy, Arubala P.2 
[1] Texas Tech Univ, Hlth Sci Ctr, Dept Orthopaed Surg, 3601 4th St,STOP 9436, Lubbock, TX 79430 USA
[2] Texas Tech Univ, 1301 Akron Ave, Lubbock, TX 79409 USA
关键词: Regenerative medicine;    Tissue engineering;    Stem cells;    Musculoskeletal disorders;    Orthopedic sports medicine;    Sex/gender;    Biomarkers;    Clinical trials;   
DOI  :  10.1016/j.bbadis.2019.165624
来源: Elsevier
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【 摘 要 】

A myriad of musculoskeletal conditions afflicts a vast number of the world's population from birth to death. Countless pathological diseases and traumatic injuries (acute and chronic) contribute to different human disabilities, causing a tremendous financial toll on the economy of healthcare. The medical field is continually searching for novel ways to combat orthopedically related conditions. The immediate goal is the restoration of anatomy then ultimately return of function in hopes of enhancing quality if not the quantity of life. Traditional methods involve surgical correction/reconstruction of skeletal deformities from fractures/soft tissue damage/ruptures or replacement/resection of degenerated joints. Modern research is currently concentrating on innovative procedures to replenish/restore the human body close to its original/natural state [1, 2].

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