Palladium and copper catalyzed Sonogashira decarboxylative coupling of aryl iodides and alkynyl carboxylic acids

TETRAHEDRON LETTERS

卷:57

Article

Maaliki, Carine¹  Chevalier, Yoan¹  Thiery, Emilie¹  Thibonnet, Jerome¹ 

[1] Univ Tours, ISP UMR 1282, UFR Sci & Tech, Parc Grandmont, F-37000 Tours, France

关键词: Palladium;    Copper;    Decarboxylative coupling;    Alkynyl carboxylic acids;    Aryl halides;   

DOI  :  10.1016/j.tetlet.2016.06.073

来源: Elsevier

【 摘 要 】

A mild procedure of palladium and copper catalyzed decarboxylative cross-coupling reaction of aryl halides and alkynyl carboxylic acids has been developed. Low molecular weight acids, to introduce small building blocks, were specifically used. This methodology is easy to implement and uses common reactants and catalysts. (C) 2016 Elsevier Ltd. All rights reserved.

【 授权许可】

Free