期刊论文详细信息
TETRAHEDRON LETTERS 卷:54
Hydrophilic pyrazine-based phosphane ligands: synthesis and application in asymmetric hydride transfer and H2-hydrogenation of acetophenone
Article
Nikishkin, Nicolai I.1  Huskens, Jurriaan1  Verboom, Willem1 
[1] Univ Twente, MESA Inst Nanotechnol, Lab Mol Nanofabricat, NL-7500 AE Enschede, Netherlands
关键词: Asymmetric catalysis;    Hydrogenation;    Phosphanes;    Pyrazine;    Reduction;   
DOI  :  10.1016/j.tetlet.2013.01.108
来源: Elsevier
PDF
【 摘 要 】

Pyrazine-based hydrophilic phosphanes are useful ligands for the ruthenium- and rhodium-catalyzed hydrogenations of acetophenone under hydride transfer and dihydrogen conditions. The effect of alcohol additives on the catalytic, enantioselective aqueous hydrogenation of acetophenone is examined with the newly developed (R,R)-DAMPYPHOS as the ligand and Rh-2(norbornadiene)(2)Cl-2 as the catalyst precursor, giving rise to higher conversions (up to quantitative) and improved enantiomeric excesses (up to 95%) of the formed 1-phenylethanol. (C) 2013 Elsevier Ltd. All rights reserved.

【 授权许可】

Free   

【 预 览 】
附件列表
Files Size Format View
10_1016_j_tetlet_2013_01_108.pdf 476KB PDF download
  文献评价指标  
  下载次数:1次 浏览次数:0次