Negishi cross-coupling of organotellurium compounds: synthesis of biaryls, aryl-, and diaryl acetylenes

TETRAHEDRON LETTERS

卷:52

Article

Stefani, Helio A.¹  Pena, Jesus M.¹  Manarin, Flavia¹  Ando, Romulo A.²  Leal, Daiana M.¹  Petragnani, Nicola² 

[1] Univ Sao Paulo, Fac Ciencias Farmaceut, Dept Farm, Sao Paulo, Brazil

[2] Univ Sao Paulo, Inst Quim, Sao Paulo, Brazil

关键词: Tellurium;    Diaryl tellurides;    Zinc;    Negishi reaction;    Aromatic rings;   

DOI  :  10.1016/j.tetlet.2011.06.025

来源: Elsevier

【 摘 要 】

A functional group tolerant palladium-catalyzed Negishi coupling of diaryl tellurides with organozinc has been developed. This methodology permits efficient preparation of biaryls, aryl acetylenes and diaryl acetylenes in moderate to good yields. A preliminary study to gain further insight into the reaction was performed using in situ ReactIR technology. (C) 2011 Elsevier Ltd. All rights reserved.

【 授权许可】

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