Utilization of the hydroxyalkylation reaction to prepare bis(benzocrown ethers)

TETRAHEDRON LETTERS

卷:53

Article

Zielinski, Matthew E.¹  Tracy, Adam F.¹  Klumpp, Douglas A.¹ 

[1] No Illinois Univ, Dept Chem & Biochem, De Kalb, IL 60115 USA

关键词: Crown compounds;    Condensation;    Heterocycles;    Electrophilic aromatic substitution;    Superacid;   

DOI  :  10.1016/j.tetlet.2012.01.049

来源: Elsevier

【 摘 要 】

The hydroxyalkylation reaction has been used to condense benzocrown ethers with various aldehydes and ketones. The condensation reactions are catalyzed by triflic or sulfuric acid. The products from the reactions are bis(benzocrown ethers) and they are formed in good yields (42-98%, 13 examples). (C) 2012 Elsevier Ltd. All rights reserved.

【 授权许可】

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