Base-free anaerobic Cu(II) catalysed aryl-nitrogen bond formations

TETRAHEDRON LETTERS

卷:45

Article

van Berkel, SS ; van den Hoogenband, A ; Terpstra, JW ; Tromp, M ; van Leeuwen, PWNM ; van Strijdonek, GPF

关键词: C-N coupling;    catalysts;    Cu(II) complexes;    solvent effects;    ligand design;   

DOI  :  10.1016/j.tetlet.2004.08.094

来源: Elsevier

【 摘 要 】

The coupling of arylboronic acids with imidazole in the presence of binuclear bis-mu-hydroxy copper(II) complexes is reported. The reactions can be performed in air as well as under nitrogen atmosphere. Reactions are carried out at ambient temperature without the need for base. The presence of water is essential for the reaction to proceed. Ligand effects on the yield and selectivity are reported. (C) 2004 Elsevier Ltd. All rights reserved.

【 授权许可】

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