Formal carbo [3+3] annulation and its application in organic synthesis

TETRAHEDRON LETTERS

卷:56

Article

Feng, Jing¹  Liu, Bo^1,2 

[1] Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China

[2] China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Jiangsu, Peoples R China

关键词: Cyclization;    Cycloaddition;    Annulation;    [3+3];    Carbocycles;   

DOI  :  10.1016/j.tetlet.2015.01.035

来源: Elsevier

【 摘 要 】

This review describes a set of approaches to generate functionalized carbocycles via [3+3] annulation and their usefulness for synthesizing frameworks of natural products. This approach relies heavily on the 1,3-dianion/1,3-dielectrophile strategy for annulations of ketones, enamines, 1,3-bis(silyl enol ethers), and other 1,3-dianionic synthons. (C) 2015 Published by Elsevier Ltd.

【 授权许可】

Free