Continuous flow iodination using an automated computer-vision controlled liquid-liquid extraction system

TETRAHEDRON LETTERS

卷:58

Article

O'Brien, Matthew¹  Cooper, Dennis A.¹  Dolan, Jonathan¹ 

[1] Keele Univ, Lennard Jones Labs, Newcastle Under Lyme ST5 5BG, Staffs, England

关键词: Open-source;    Automation;    Computer-vision;    Continuous-flow;    Iodination;   

DOI  :  10.1016/j.tetlet.2017.01.029

来源: Elsevier

【 摘 要 】

A dynamic computer-vision control system incorporating open-source software technologies (Python, OpenCV) was used to automate a gravity based in-line liquid-liquid extraction during the iodination of enaminones in continuous flow. The system was able to cope with significant colouration of the organic reaction stream and with significant volume/flow changes in the aqueous and organic phase streams due to extraction of the water soluble acetonitrile co-solvent. (C) 2017 Elsevier Ltd. All rights reserved.

【 授权许可】

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