AlCl3-promoted reaction of cycloalkanones with hydrazones: a convenient direct synthesis of 4,5,6,7-tetrahydro-1H-indazoles and their analogues

TETRAHEDRON LETTERS

卷:60

Article

Laroum, Rima¹  Berree, Fabienne²  Roisnel, Thierry²  Dorcet, Vincent²  Carboni, Bertrand²  Debache, Abdelmadjid¹ 

[1] Univ Freres Mentouri Constantine, Lab Synth Mol Interets Biol, Constantine 25000, Algeria

[2] Univ Rennes, CNRS, UMR 6226, ISCR, F-35000 Rennes, France

关键词: Cycloalkanones;    Hydrazones;    Tetrahydroindazoles;    Aluminum chloride;   

DOI  :  10.1016/j.tetlet.2019.150988

来源: Elsevier

【 摘 要 】

The AlCl3-promoted reactions of cycloalkanones with hydrazones are described. This approach represents a mild and operationally simple method to access 2,3-diaryl-4,5,6,7-tetrahydro-1H-indazoles and their analogues in good to moderate yields. (C) 2019 Elsevier Ltd. All rights reserved.

【 授权许可】

Free