Regioselective 2′-O-debenzoylation of 2′,3′-di-O-benzoyl threose nucleosides

TETRAHEDRON LETTERS

卷:54

Article

Jang, Mi-Yeon¹  Froeyen, Matheus¹  Herdewijn, Piet¹ 

[1] Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium

关键词: Threose;    Regioselective debenzoylation;    Potassium tert-butoxide;    TNA;    2 '-Modified threose nucleosides;   

DOI  :  10.1016/j.tetlet.2013.08.117

来源: Elsevier

【 摘 要 】

A simple and convenient procedure for the regioselective 2'-0-debenzoylation of 2',3'-di-O-benzoyl threose nucleosides has been achieved successfully affording 3'-0-benzoyl threose nucleosides, which are useful starting material synthons for the synthesis of modified threose nucleosides for different purposes. (C) 2013 Published by Elsevier Ltd.

【 授权许可】

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