Simple and efficient synthesis of 2,5-anhydro-D-glucitol

TETRAHEDRON LETTERS

卷:54

Article

Aragao-Leoneti, Valquiria¹  Carvalho, Ivone¹ 

[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040930 Ribeirao Preto, Brazil

关键词: Carbohydrate synthesis;    Glucitol;    Microwave-assisted reaction;   

DOI  :  10.1016/j.tetlet.2012.12.062

来源: Elsevier

【 摘 要 】

The synthesis of 2,5-anhydro-D-glucitol is described via intramolecular cyclization of diepoxide using ammonium formate in MeOH by a microwave-assisted reaction. The overall yield was 32% from D-mannitol derivative involving seven steps. (C) 2012 Elsevier Ltd. All rights reserved.

【 授权许可】

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