No effect of 14 day consumption of whole grain diet compared to refined grain diet on antioxidant measures in healthy, young subjects: a pilot study

Nutrition Journal

Research

Joanne Slavin¹  Lynda Enright¹ 

[1] Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, 55108, St Paul, MN, USA;

关键词: Antioxidant Activity;    Trolox;    Antioxidant Potential;    Thiobarbituric Acid Reactive Substance;    Oxygen Radical Absorbance Capacity;   

DOI  :  10.1186/1475-2891-9-12

 received in 2009-08-21, accepted in 2010-03-19,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundEpidemiological evidence supports that a diet high in whole grains is associated with lowered risk of chronic diseases included coronary heart disease, obesity, type 2 diabetes, and some types of cancer. One potential mechanism for the protective properties of whole grains is their antioxidant content. The aim of this study was to compare differences in antioxidant measures when subjects consumed either refined or whole grain diets.MethodsTwenty healthy subjects took part in a randomized, crossover dietary intervention study. Subjects consumed either a refined grain or whole grain diet for 14 days and then the other diet for the next 14 days. Male subjects consumed 8 servings of grains per day and female subjects consumed 6 servings of grains per day. Blood and urine samples were collected at the end of each diet. Antioxidant measures included oxygen radical absorbance capacity (ORAC) in blood, and isoprostanes and thiobarbituric acid reactive substances (TBARS) in urine.ResultsThe whole grain diet was significantly higher in dietary fiber, vitamin B6, folate, selenium, copper, zinc, iron, magnesium and cystine compared to the refined grain diet. Despite high intakes of whole grains, no significant differences were seen in any of the antioxidant measures between the refined and whole grain diets.ConclusionsNo differences in antioxidant measures were found when subjects consumed whole grain diets compared to refined grain diets.

【 授权许可】

CC BY   
© Enright and Slavin; licensee BioMed Central Ltd. 2010