Effect of the yellow passion fruit peel flour (Passiflora edulis f. flavicarpa deg.) in insulin sensitivity in type 2 diabetes mellitus patients

Nutrition Journal

Research

Armando UO Sabaa-Srur¹  Margareth de Fatima FM Diniz²  Maria do Socoro Ramos de Queiroz³  Maria Auxiliadora Lins da Cunha³  Josimar dos Santos Medeiros³  Silvana Cristina dos Santos³  Daniele Idalino Janebro⁴ 

[1] Department of Nutrition, Federal University of Rio de Janeiro, 21949-900, Rio de Janeiro, PB, Brazil;Department of Pharmacy, Paraíba State University, 58051-970, Campina Grande, PB, Brazil;Department of Pharmacy, Paraíba State University, 58429-600, Campina Grande, PB, Brazil;Maurício de Nassau College, 58410-050, Campina Grande, PB, Brazil;

关键词: Pectin;    Dietary Fiber;    Passion Fruit;    Soluble Fiber;    Soluble Dietary Fiber;   

DOI  :  10.1186/1475-2891-11-89

 received in 2012-04-25, accepted in 2012-10-16,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundA study with the yellow passion fruit peel flour showed positive action in blood glucose control as therapies’ adjuvant in patients with type 2 diabetes mellitus. Therefore, we evaluated its effect on insulin sensitivity since there is a quest for studies that focus at better understanding of insulin resistance aspects in diabetic patients. Furthermore its relationship with chronic complications can also give good prospects for alternative treatments.MethodsA total of 43 type 2 diabetes volunteers (28 females and 15 males) ingested 30 g/day of the yellow passion fruit peel flour for two months. The levels of blood glucose and fasting insulin, HOMA index and glycated hemoglobin were measured for each patient before and after dietary supplementation.ResultsThere was a significant difference in the fasting blood glucose values (P = 0.000) and glycated hemoglobin (P = 0.032) after supplementation. It was also seen a reduction in HOMA IR (P = 0.005) in the supplemented group, however it was not observed changes in insulin values for females. HOMA beta (P = 0.000) showed significant increase in its values for the studied group.ConclusionsThe supplementation used decreased insulin resistance in type 2 diabetic patients, suggesting a positive action in blood glucose control as adjuvant therapy in conventional treatments.

【 授权许可】

CC BY   
© de Queiroz et al.; licensee BioMed Central Ltd. 2012