Soft tissue perineurioma of the tongue: report of a case and review of the literature

World Journal of Surgical Oncology

Case Report

Yao-xiang Xu¹  Wen-lin Xiao¹  Ling-fa Xue² 

[1] Department of Oral and Maxillofacial Surgery, The Medical School Hospital of Qingdao University, No. 1677, Wutaishan Road, 266555, Qingdao, People’s Republic of China;Department of Pathology, The Medical School Hospital of Qingdao University, No. 1677, Wutaishan Road, Qingdao, People’s Republic of China;

关键词: Perineurioma;    Soft tissue;    Tongue;   

DOI  :  10.1186/1477-7819-12-11

 received in 2013-07-20, accepted in 2013-12-23,  发布年份 2014

来源: Springer

【 摘 要 】

Perineurioma is a rare benign tumor of the peripheral nervous system distinct from schwannomas and neurofibromas. It may be intraneural or extraneural (in the soft tissue). Extraneural soft tissue perineuriomas are uncommon; rare cases have been reported in the oral cavity. We present a case of soft tissue perineurioma in the tip of the tongue. The tumor was characterized by slender spindle cells, arranged in short fascicles or whorls, and focal areas showing a distinct storiform pattern. Tumor cells showed the immunohistochemical profile of perineurial cells, including epithelial membrane antigen. Smooth muscle actin, S-100, and CD34 were not expressed by the tumor cells. The tumor was surgically excised and in 2 years there has been no recurrence. Knowledge of the tumor in the oral cavity is important to reach a correct diagnosis and to avoid unnecessary aggressive local excision.

【 授权许可】

CC BY   
© Xiao et al.; licensee BioMed Central Ltd. 2014