World Journal of Surgical Oncology | |
Soft tissue perineurioma of the tongue: report of a case and review of the literature | |
Yao-xiang Xu1  Ling-fa Xue2  Wen-lin Xiao1  | |
[1] Department of Oral and Maxillofacial Surgery, The Medical School Hospital of Qingdao University, No. 1677, Wutaishan Road, Qingdao 266555, People’s Republic of China;Department of Pathology, The Medical School Hospital of Qingdao University, No. 1677, Wutaishan Road, Qingdao, People’s Republic of China | |
关键词: Tongue; Soft tissue; Perineurioma; | |
Others : 820569 DOI : 10.1186/1477-7819-12-11 |
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received in 2013-07-20, accepted in 2013-12-23, 发布年份 2014 | |
【 摘 要 】
Perineurioma is a rare benign tumor of the peripheral nervous system distinct from schwannomas and neurofibromas. It may be intraneural or extraneural (in the soft tissue). Extraneural soft tissue perineuriomas are uncommon; rare cases have been reported in the oral cavity. We present a case of soft tissue perineurioma in the tip of the tongue. The tumor was characterized by slender spindle cells, arranged in short fascicles or whorls, and focal areas showing a distinct storiform pattern. Tumor cells showed the immunohistochemical profile of perineurial cells, including epithelial membrane antigen. Smooth muscle actin, S-100, and CD34 were not expressed by the tumor cells. The tumor was surgically excised and in 2 years there has been no recurrence. Knowledge of the tumor in the oral cavity is important to reach a correct diagnosis and to avoid unnecessary aggressive local excision.
【 授权许可】
2014 Xiao et al.; licensee BioMed Central Ltd.
【 预 览 】
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20140712050316514.pdf | 1284KB | download | |
Figure 3. | 173KB | Image | download |
Figure 2. | 132KB | Image | download |
Figure 1. | 76KB | Image | download |
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