A case report of retroperitoneal pararenal Castleman’s disease associated with myasthenia gravis

World Journal of Surgical Oncology

Case Report

Shan-Wen Chen¹  Song-Liang Cai¹  Bai-Yan Jin¹  Shuai Wang² 

[1] The first affiliated hospital of Zhejiang University School of Medcine, Qingchun Road NO.79, 310003, Hangzhou, Zhejiang, China;The fourth affiliated hospital of Zhejiang University School of Medcine, Shangcheng Road NO.N1, 322000, Yiwu, Zhejiang, China;

关键词: Castleman’s disease;    Myasthenia gravis;    Myasthenic crisis;    Retroperitoneum;    Surgery;   

DOI  :  10.1186/1477-7819-12-331

 received in 2014-04-29, accepted in 2014-10-20,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundCastleman’s disease (CD) is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue. The combination of an occurrence of retroperitoneal pararenal CD with myasthenia gravis (MG) is extremely rare.Case presentationThe patient was admitted to our hospital for investigation of a retroperitoneal pararenal tumor which had been coincidentally diagnosed at a local hospital where he was admitted because of MG. The patient subsequently underwent an exploratory laparotomy and suffered from postoperative myasthenic crisis. Pathological examination revealed a left retroperitoneal mass of CD (hyaline vascular type). There was no recurrence of disease found after 7 months.ConclusionsCD with MG is a rare condition. Postoperative myasthenic crisis is a severe complication. The possibility of its occurrence must be in physicians’ minds and the risk of postoperative myasthenic crisis must be carefully considered when evaluating MG patients undergoing surgery.

【 授权许可】

Unknown   
© Wang et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.