A case report of retroperitoneal pararenal Castleman’s disease associated with myasthenia gravis

World Journal of Surgical Oncology

Bai-Yan Jin²  Song-Liang Cai²  Shan-Wen Chen²  Shuai Wang¹ 

[1] The fourth affiliated hospital of Zhejiang University School of Medcine, Shangcheng Road NO.N1, Yiwu, Zhejiang 322000, China;The first affiliated hospital of Zhejiang University School of Medcine, Qingchun Road NO.79, Hangzhou, Zhejiang 310003, China

关键词: Surgery;    Retroperitoneum;    Myasthenic crisis;    Myasthenia gravis;    Castleman’s disease;   

Others  :  1147533
DOI  :  10.1186/1477-7819-12-331

 received in 2014-04-29, accepted in 2014-10-20,  发布年份 2014

【 摘 要 】

Background

Castleman’s disease (CD) is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue. The combination of an occurrence of retroperitoneal pararenal CD with myasthenia gravis (MG) is extremely rare.

Case presentation

The patient was admitted to our hospital for investigation of a retroperitoneal pararenal tumor which had been coincidentally diagnosed at a local hospital where he was admitted because of MG. The patient subsequently underwent an exploratory laparotomy and suffered from postoperative myasthenic crisis. Pathological examination revealed a left retroperitoneal mass of CD (hyaline vascular type). There was no recurrence of disease found after 7 months.

Conclusions

CD with MG is a rare condition. Postoperative myasthenic crisis is a severe complication. The possibility of its occurrence must be in physicians’ minds and the risk of postoperative myasthenic crisis must be carefully considered when evaluating MG patients undergoing surgery.

【 授权许可】

   
2014 Wang et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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