Hemoglobin A1c improvements and better diabetes-specific quality of life among participants completing diabetes self-management programs: A nested cohort study

Health and Quality of Life Outcomes

Research

Abhinav Khanna¹  Amber L Bush²  Aanand D Naik²  Richard L Street³  J Michael Swint⁴  Melissa Fleschler Peskin⁵ 

[1] Baylor College of Medicine, 1 Baylor Plaza, 77030, Houston, TX, USA;Baylor College of Medicine, 1 Baylor Plaza, 77030, Houston, TX, USA;Houston Health Services Research and Development, Center of Excellence, Michael E. DeBakey VA Medical Center (152), 2002 Holcombe Blvd, 77030, Houston, TX, USA;Baylor College of Medicine, 1 Baylor Plaza, 77030, Houston, TX, USA;Houston Health Services Research and Development, Center of Excellence, Michael E. DeBakey VA Medical Center (152), 2002 Holcombe Blvd, 77030, Houston, TX, USA;Department of Communication, Office: 205C Bolton, Texas A&M University, 77843-4234, College Station, TX, USA;University of Texas School of Public Health, 1200 Hermann Pressler, Room E933, 77030, Houston, TX, USA;University of Texas School of Public Health, 7000 Fannin, Suite 2648, 77030, Houston, TX, USA;

关键词: Diabetes-specific quality of life;    Diabetes;    Quality of life;    Diabetes-39;    Self-management;    Hemoglobin A;   

DOI  :  10.1186/1477-7525-10-48

 received in 2012-01-18, accepted in 2012-05-14,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundNumerous primary care innovations emphasize patient-centered processes of care. Within the context of these innovations, greater understanding is needed of the relationship between improvements in clinical endpoints and patient-centered outcomes. To address this gap, we evaluated the association between glycosylated hemoglobin (HbA1c) and diabetes-specific quality of life among patients completing diabetes self-management programs.MethodsWe conducted a retrospective cohort study nested within a randomized comparative effectiveness trial of diabetes self-management interventions in 75 diabetic patients. Multiple linear regression models were developed to examine the relationship between change in HbA1c from baseline to one-year follow-up and Diabetes-39 (a diabetes-specific quality of life measure) at one year.ResultsHbA1c levels improved for the overall cohort from baseline to one-year follow-up (t (74) = 3.09, p = .0029). One-year follow up HbA1c was correlated with worse overall quality of life (r = 0.33, p = 0.004). Improvements in HbA1c from baseline to one-year follow-up were associated with greater D-39 diabetes control (β = 0.23, p = .04) and D-39 sexual functioning (β = 0.25, p = .03) quality of life subscales.ConclusionsImprovements in HbA1c among participants completing a diabetes self-management program were associated with better diabetes-specific quality of life. Innovations in primary care that engage patients in self-management and improve clinical biomarkers, such as HbA1c, may also be associated with better quality of life, a key outcome from the patient perspective.

【 授权许可】

Unknown   
© Khanna et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.