Hemoglobin A1c improvements and better diabetes-specific quality of life among participants completing diabetes self-management programs: A nested cohort study

Health and Quality of Life Outcomes

Aanand D Naik³  Richard L Street²  Melissa Fleschler Peskin⁴  J Michael Swint¹  Amber L Bush³  Abhinav Khanna⁵ 

[1] University of Texas School of Public Health, 1200 Hermann Pressler, Room E933, Houston, TX, 77030, USA;Department of Communication, Office: 205C Bolton, Texas A&M University, College Station, TX, 77843-4234, USA;Houston Health Services Research and Development, Center of Excellence, Michael E. DeBakey VA Medical Center (152), 2002 Holcombe Blvd, Houston, TX, 77030, USA;University of Texas School of Public Health, 7000 Fannin, Suite 2648, Houston, TX, 77030, USA;Baylor College of Medicine, 1 Baylor Plaza, Houston, TX, 77030, USA

关键词: Hemoglobin A_1c;    Self-management;    Diabetes-39;    Quality of life;    Diabetes;    Diabetes-specific quality of life;   

Others  :  825658
DOI  :  10.1186/1477-7525-10-48

 received in 2012-01-18, accepted in 2012-05-14,  发布年份 2012

【 摘 要 】

Background

Numerous primary care innovations emphasize patient-centered processes of care. Within the context of these innovations, greater understanding is needed of the relationship between improvements in clinical endpoints and patient-centered outcomes. To address this gap, we evaluated the association between glycosylated hemoglobin (HbA_1c) and diabetes-specific quality of life among patients completing diabetes self-management programs.

Methods

We conducted a retrospective cohort study nested within a randomized comparative effectiveness trial of diabetes self-management interventions in 75 diabetic patients. Multiple linear regression models were developed to examine the relationship between change in HbA_1c from baseline to one-year follow-up and Diabetes-39 (a diabetes-specific quality of life measure) at one year.

Results

HbA_1c levels improved for the overall cohort from baseline to one-year follow-up (t (74) = 3.09, p = .0029). One-year follow up HbA_1c was correlated with worse overall quality of life (r = 0.33, p = 0.004). Improvements in HbA_1c from baseline to one-year follow-up were associated with greater D-39 diabetes control (β = 0.23, p = .04) and D-39 sexual functioning (β = 0.25, p = .03) quality of life subscales.

Conclusions

Improvements in HbA_1c among participants completing a diabetes self-management program were associated with better diabetes-specific quality of life. Innovations in primary care that engage patients in self-management and improve clinical biomarkers, such as HbA_1c, may also be associated with better quality of life, a key outcome from the patient perspective.

【 授权许可】

   
2012 Khanna et al.; licensee BioMed Central Ltd.

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