Dietary and physical activity adaptations to alternate day modified fasting: implications for optimal weight loss

Nutrition Journal

Research

Sally Freels¹  Surabhi Bhutani²  Monica C Klempel²  Krista A Varady²  Marian Fitzgibbon³ 

[1] Department of Biostatistics, University of Illinois at Chicago, Chicago, IL, USA;Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA;Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA;

关键词: Energy Intake;    Obese Subject;    Calorie Restriction;    Food Record;    Habitual Physical Activity;   

DOI  :  10.1186/1475-2891-9-35

 received in 2010-04-29, accepted in 2010-09-03,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundAlternate day modified fasting (ADMF) is an effective strategy for weight loss in obese adults.ObjectiveThe objective of this study was to examine the dietary and physical activity adaptations that occur during short-term ADMF, and to determine how these modulations affect rate of weight loss.MethodsSixteen obese subjects (12 women/4 men) completed a 10-week trial consisting of 3 phases: 1) 2-week control phase, 2) 4-week ADMF controlled feeding phase, and 3) 4-week ADMF self-selected feeding phase.ResultsBody weight decreased (P < 0.001) by 5.6 ± 1.0 kg post-treatment. Energy intake on the fast day was 26 ± 3% of baseline needs (501 ± 28 kcal/d). No hyperphagic response occurred on the feed day (95 ± 6% of baseline needs consumed, 1801 ± 226 kcal/d). Daily energy restriction (37 ± 7%) was correlated to rate of weight loss (r = 0.42, P = 0.01). Dietary fat intake decreased (36% to 33% of kcal, P < 0.05) with dietary counseling, and was related to rate of weight loss (r = 0.38, P = 0.03). Hunger on the fast day decreased (P < 0.05) by week 2, and remained low. Habitual physical activity was maintained throughout the study (fast day: 6416 ± 851 steps/d; feed day: 6569 ± 910 steps/d).ConclusionThese findings indicate that obese subjects quickly adapt to ADMF, and that changes in energy/macronutrient intake, hunger, and maintenance of physical activity play a role in influencing rate of weight loss by ADMF.

【 授权许可】

Unknown   
© Klempel et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.