Dietary whey protein lessens several risk factors for metabolic diseases: a review

Lipids in Health and Disease

Review

Gustavo D Pimentel¹  Gabriela TD Sousa²  José C Rosa²  Lila M Oyama³  Erick P de Oliveira⁴  Ronaldo V Santos⁵  Fábio S Lira⁶ 

[1] Departamento de Clínica Médica, Universidade Estadual de Campinas (UNICAMP), 13083-970, Campinas/SP, MA, Brazil;Departamento de Fisiologia e Biofísica, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, SP, Brazil;Departamento de Fisiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil;Departamento de Patologia, Universidade Estadual Paulista (UNESP), Botucatu, SP, Brazil;Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil;Laboratório de Bioquímica e Fisiologia do Exercício, Universidade do Extremo Sul Catarinense, Criciúma/SC, Brazil;

关键词: Whey protein;    Obesity;    Type 2 diabetes mellitus;    Appetite;    Inflammation;    Hypertension.;   

DOI  :  10.1186/1476-511X-11-67

 received in 2012-02-14, accepted in 2012-06-07,  发布年份 2012

来源: Springer

【 摘 要 】

Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.

【 授权许可】

Unknown   
© Souza et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.