Dietary whey protein lessens several risk factors for metabolic diseases: a review

Lipids in Health and Disease

Gustavo D Pimentel³  Ronaldo V Santos⁴  Lila M Oyama²  Erick P de Oliveira¹  José C Rosa⁶  Fábio S Lira⁵  Gabriela TD Sousa⁶ 

[1] Departamento de Patologia, Universidade Estadual Paulista (UNESP), Botucatu/SP, Brazil;Departamento de Fisiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo/SP, Brazil;Departamento de Clínica Médica, Universidade Estadual de Campinas (UNICAMP), Campinas/SP, MA:, 13083-970, Brazil;Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo/SP, Brazil;Laboratório de Bioquímica e Fisiologia do Exercício, Universidade do Extremo Sul Catarinense, Criciúma/SC, Brazil;Departamento de Fisiologia e Biofísica, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo/SP, Brazil

关键词: Hypertension.;    Inflammation;    Appetite;    Type 2 diabetes mellitus;    Obesity;    Whey protein;   

Others  :  1160290
DOI  :  10.1186/1476-511X-11-67

 received in 2012-02-14, accepted in 2012-06-07,  发布年份 2012

【 摘 要 】

Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.

【 授权许可】

   
2012 Souza et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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