The prevalence of malaria among HIV seropositive individuals and the impact of the co- infection on their hemoglobin levels

Annals of Clinical Microbiology and Antimicrobials

Research

Sammy CK Tay¹  Kingsley Badu²  Anthony A Mensah³  Stephen Y Gbedema⁴ 

[1] Department of Clinical Microbiology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana;Department of Immunology, Noguchi Memorial Institute for Medical Research, College of Health Science, University of Ghana, Accra, Ghana;Department of Microbiology, Holy Family Hospital Techiman, Techiman, Ghana;Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana;

关键词: HIV/AIDS;    CD cells;    Malaria co-infection;    Anaemia;    Anti-retroviral;   

DOI  :  10.1186/s12941-015-0064-6

 received in 2014-06-02, accepted in 2015-01-12,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundMalaria and HIV/AIDS are the two most common infections in sub-Sahara Africa. There are hypotheses and study reports on the possible association between these two infections, hence the prevalence and outcome of their co-infection in an endemic population will be important in defining healthcare strategies. A cross sectional study was carried out at the Holy Family Hospital in Techiman, Ghana, between November 2011 and January 2012, to determine the prevalence of malaria among HIV sero-positive patients and its impact on hemoglobin levels.MethodA total of 400 HIV sero-positive participants (292 females and 108 males) aged between 1 and 73 years were randomly sampled for the study. A questionnaire was administered and 2 ml of venous blood samples were drawn for malaria parasites detection, CD4 count and haemoglobin level estimations.ResultsMalaria parasites were detected in 47 (11.75%) of the participants. There was no statistically significant difference between the malaria prevalence rate of females (12.1%) and males (10.2%) P = 0.6047. An overall anaemia prevalence of 67% was observed. Among participants with malaria the anaemia prevalence was 93.6%. The CD4 cell count of all the participants ranged between 3 and 1604 cells/μl with a mean of 386.2 (±274.3) cells/μl. Participants with malaria had CD4 cell count ranged 3 and 512 Cells/μl with the mean being 186.33 (±133.49) Cells/μl. Out of 377 participants (all above 15 years) interviewed on knowledge of malaria transmission and prevention, 87.0% had knowledge on transmission but only 8.5% use in bed nets.ConclusionIt was revealed that almost all the patients with malaria infection were anemic.

【 授权许可】

CC BY   
© Tay et al.; licensee BioMed Central. 2015