A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance

Review

Peter D. Gatehouse¹  David N. Firmin¹  Merlin J. Fair¹  Edward V. R. DiBella² 

[1] National Heart & Lung Institute, Imperial College London, London, UK;Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK;Utah Center for Advanced Imaging Research, University of Utah, Salt Lake City, UT, USA;

关键词: Myocardial perfusion;    3D;    Whole heart;    Cardiovascular magnetic resonance;   

DOI  :  10.1186/s12968-015-0162-9

 received in 2014-08-26, accepted in 2015-06-23,  发布年份 2015

来源: Springer

【 摘 要 】

A comprehensive review is undertaken of the methods available for 3D whole-heart first-pass perfusion (FPP) and their application to date, with particular focus on possible acceleration techniques. Following a summary of the parameters typically desired of 3D FPP methods, the review explains the mechanisms of key acceleration techniques and their potential use in FPP for attaining 3D acquisitions. The mechanisms include rapid sequences, non-Cartesian k-space trajectories, reduced k-space acquisitions, parallel imaging reconstructions and compressed sensing. An attempt is made to explain, rather than simply state, the varying methods with the hope that it will give an appreciation of the different components making up a 3D FPP protocol. Basic estimates demonstrating the required total acceleration factors in typical 3D FPP cases are included, providing context for the extent that each acceleration method can contribute to the required imaging speed, as well as potential limitations in present 3D FPP literature. Although many 3D FPP methods are too early in development for the type of clinical trials required to show any clear benefit over current 2D FPP methods, the review includes the small but growing quantity of clinical research work already using 3D FPP, alongside the more technical work. Broader challenges concerning FPP such as quantitative analysis are not covered, but challenges with particular impact on 3D FPP methods, particularly with regards to motion effects, are discussed along with anticipated future work in the field.

【 授权许可】

CC BY   
© Fair et al. 2015