期刊论文详细信息
BMC Cardiovascular Disorders
Comparison of global myocardial strain assessed by cardiovascular magnetic resonance tagging and feature tracking to infarct size at predicting remodelling following STEMI
Research Article
Sheraz A. Nazir1  Florence Y. Lai1  Gerald P. McCann1  Jayanth R. Arnold1  Jamal N. Khan1  Iain B. Squire1  Naveed A. Razvi2  Nathan Price3  Abhishek M. Shetye4 
[1] Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Road, LE3 9QF, Leicester, UK;Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Road, LE3 9QF, Leicester, UK;Ipswich Hospital NHS trust, IP4 5PD, Ipswich, UK;Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Road, LE3 9QF, Leicester, UK;Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, LS2 9JT, Leeds, UK;Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Road, LE3 9QF, Leicester, UK;Oxford University Hospitals NHS Trust, OX3 9DU, Oxford, UK;
关键词: Cardiac magnetic resonance;    Tagging;    Feature tracking;    Strain;    Remodelling;    ST-elevation myocardial infarction;   
DOI  :  10.1186/s12872-016-0461-6
 received in 2016-09-21, accepted in 2016-12-23,  发布年份 2017
来源: Springer
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【 摘 要 】

BackgroundTo determine if global strain parameters measured by cardiovascular magnetic resonance (CMR) acutely following ST-segment Elevation Myocardial Infarction (STEMI) predict adverse left ventricular (LV) remodelling independent of infarct size (IS).MethodsSixty-five patients with acute STEMI (mean age 60 ± 11 years) underwent CMR at 1–3 days post-reperfusion (baseline) and at 4 months. Global peak systolic circumferential strain (GCS), measured by tagging and Feature Tracking (FT), and global peak systolic longitudinal strain (GLS), measured by FT, were calculated at baseline, along with IS. On follow up scans, volumetric analysis was performed to determine the development of adverse remodelling – a composite score based on development of either end-diastolic volume index [EDVI] ≥20% or end-systolic volume index [ESVI] ≥15% at follow-up compared to baseline.ResultsThe magnitude of GCS was higher when measured using FT (−21.1 ± 6.3%) than with tagging (−12.1 ± 4.3; p < 0.001 for difference). There was good correlation of strain with baseline LVEF (r 0.64–to 0.71) and IS (ρ -0.62 to–0.72). Baseline strain parameters were unable to predict development of adverse LV remodelling. Only baseline IS predicted adverse remodelling – Odds Ratio 1.05 (95% CI 1.01–1.10, p = 0.03), area under the ROC curve 0.70 (95% CI 0.52–0.87, p = 0.04).ConclusionBaseline global strain by CMR does not predict the development of adverse LV remodelling following STEMI.

【 授权许可】

CC BY   
© The Author(s). 2017

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