Direct comparison of multilayer left ventricular global longitudinal strain using CMR feature tracking and speckle tracking echocardiography

BMC Cardiovascular Disorders

Saikrishna Ananthapadmanabhan¹  Giau Vo²  Tuan Nguyen²  Hany Dimitri²  James Otton² 

[1] Faculty of Medicine, University of New South Wales, 2052, Sydney, Australia;Faculty of Medicine, University of New South Wales, 2052, Sydney, Australia;Cardiology Department, Liverpool Hospital, 2170, Liverpool, Sydney, Australia;

关键词: Cardiac magnetic resonance;    Feature tracking;    Speckle tracking echocardiography;    Multilayer;   

DOI  :  10.1186/s12872-021-01916-8

来源: Springer

【 摘 要 】

BackgroundCardiac magnetic resonance feature tracking (CMR-FT) and speckle tracking echocardiography (STE) are well-established strain imaging modalities. Multilayer strain measurement permits independent assessment of endocardial and epicardial strain. This novel and layer specific approach to evaluating myocardial deformation parameters may provide greater insight into cardiac contractility when compared to whole-layer strain analysis. The aim of this study is to validate CMR-FT as a tool for multilayer strain analysis by providing a direct comparison between multilayer global longitudinal strain (GLS) values between CMR-FT and STE.MethodsWe studied 100 patients who had an acute myocardial infarction (AMI), who underwent CMR imaging and echocardiogram at baseline and follow-up (48 ± 13 days). Dedicated tissue tracking software was used to analyse single- and multi-layer GLS values for CMR-FT and STE.ResultsCorrelation coefficients for CMR-FT and STE were 0.685, 0.687, and 0.660 for endocardial, epicardial, and whole-layer GLS respectively (all p < 0.001). Bland Altman analysis showed good inter-modality agreement with minimal bias. The absolute limits of agreement in our study were 6.4, 5.9, and 5.5 for endocardial, whole-layer, and epicardial GLS respectively. Absolute biases were 1.79, 0.80, and 0.98 respectively. Intraclass correlation coefficient (ICC) values showed moderate agreement with values of 0.626, 0.632, and 0.671 respectively (all p < 0.001).ConclusionThere is good inter-modality agreement between CMR-FT and STE for whole-layer, endocardial, and epicardial GLS, and although values should not be used interchangeably our study demonstrates that CMR-FT is a viable imaging modality for multilayer strain

【 授权许可】

CC BY