Long-term exposures to ambient particulate matter and ozone pollution with lower extremity deep vein thrombosis after surgical operations: a retrospective case-control study in Beijing, China

BMC Public Health

Research

Yong Wang¹  Furong Deng²  Shaowei Wu³  Qin Xiong⁴  Zhihu Xu⁵  Xuezhao Ji⁵  Wanzhou Wang⁶  Min Zhang⁷  Benqiang Rao⁸ 

[1] Beijing First Aid Center, 100031, Beijing, China;Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, 100191, Beijing, China;Department of Occupational and Environmental Health, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, China;Education Department, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;Education Department, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, 100191, Beijing, China;Education Department, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, 100191, Beijing, China;National Institute of Health Data Science, Peking University Health Science Center, Beijing, China;Medical Insurance Management Office, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;Second Ward of Gastrointestinal Surgery, Beijing Shijitan Hospital, Capital Medical University, 100038, Beijing, China;

关键词: Ambient air pollution;    Fine particulate matter;    Inhalable particulate matter;    Ozone;    Venous thromboembolism;    Deep vein thrombosis;   

DOI  :  10.1186/s12889-023-16882-3

 received in 2023-05-10, accepted in 2023-10-03,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundLower extremity deep vein thrombosis (LEDVT) after surgical operations is a common and fatal disease leading to unfavorable outcomes including death. Nevertheless, there has been insufficient evidence on the associations between ambient air pollution and LEDVT, particularly studies from developing regions.MethodsBased on 302 LEDVT cases and 302 controls in a general hospital in Beijing, China, this unmatched retrospective case-control study investigated the associations of fine particulate matter (PM2.5), inhalable particulate matter (PM10), and ozone (O3) with odds of LEDVT.ResultsPer 10 μg/m3 increase in PM2.5, PM10, and O3 at 3-month, 6-month, and 2-year average was associated with increased LEDVT odds [odds ratios (ORs) for PM2.5: 1.10 (95%CI: 1.05, 1.14), 1.14 (95%CI: 1.09, 1.18), and 1.30 (95%CI: 1.06, 1.61); ORs for PM10: 1.06 (95%CI: 1.02, 1.10), 1.12 (95%CI: 1.08, 1.16), and 1.29 (95%CI: 1.03, 1.61); ORs for O3: 1.00 (95%CI: 0.96, 1.04), 1.16 (95%CI: 1.02, 1.31), and 2.08 (95%CI: 1.03, 4.18), respectively]. The stratified analyses, exposure-responses curves, and sensitivity analyses further highlighted the robustness of our findings.ConclusionsLong-term exposures to ambient PM2.5, PM10, and O3 may increase the risk of LEDVT in patients after surgical operations. The results may be implicated in the prevention and control of adverse clinical outcomes of surgical patients associated with ambient air pollution.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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