Hybrid delivery of cluster-set resistance training for individuals previously treated for lung cancer: the results of a single-arm feasibility trial

Pilot and Feasibility Studies

Research

K. L. Kendall¹  C. Latella¹  K. K. McDonnell²  O. L. Owens³  J. M. Dawson⁴  C. M. Fairman⁴  A. R. Schumpp⁴  M. T. Jones⁵  C. M. J. Peddle-McIntyre⁶  L. Marcotte⁷  J. Steele⁸ 

[1] Centre for Human Performance, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Australia;College of Nursing, University of South Carolina, Columbia, USA;College of Social Work, University of South Carolina, Columbia, USA;Department of Exercise Science, University of South Carolina, Columbia, USA;Department of Exercise Science, University of South Carolina, Columbia, USA;Department of Kinesiology, The University of Alabama, Tuscaloosa, USA;Exercise Medicine Research Institute, School of Medical and Health Science, Edith Cowan University, Joondalup, Australia;Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada;Faculty of Sport, Health, and Social Science, Solent University, Southampton, UK;

关键词: Resistance training;    Lung cancer;    Cluster sets;    Dyspnea;    Fatigue;    Physical fitness;    Quality of life;   

DOI  :  10.1186/s40814-023-01405-z

 received in 2023-04-06, accepted in 2023-10-06,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundIndividuals with non-small cell lung cancer (NSCLC) are burdened by long-lasting symptoms (e.g., dyspnea and fatigue) post-treatment. These symptoms often reduce physical activity levels and increase the risk of functional decline. Though we have previously proposed cluster-set resistance training to mitigate symptom burden in lung cancer, there is currently no data on the feasibility or acceptability of this mode of exercise in cancer. Therefore, the purpose of this study was to investigate the feasibility and acceptability of a hybrid-delivery home-based cluster-set resistance training program in individuals with NSCLC stages I–III (i.e., early stage).MethodsThis study aimed to recruit individuals with NSCLC stages I–III post-treatment to participate in 8 weeks of home-based resistance training, 3 days per week. The program included supervised sessions in the participants’ homes and virtual supervision via videoconferencing. The primary outcome measure of feasibility was evaluated through recruitment, retention, and intervention fidelity (i.e., proportion of exercise completed, relative to what was prescribed). Intervention acceptability (i.e., ease and quality of virtual delivery, level of difficulty, and home-based approach) was assessed using a 4-point Likert-type scale from “strongly disagree” to “strongly agree”.ResultsFourteen participants were recruited over a 6-month period, with 11 completing the intervention (2 withdrew due to unrelated illness, 1 withdrew due to requiring active treatment), yielding a retention rate of 79%. Characteristics of the participants who completed the intervention (n = 11) were as follows: mean age: 71 ± 10 years, mean BMI: 29.1 ± 6.5, and average time since diagnosis was 62 ± 51 months. Of completers, 27% were male, and 36% were Black; 10 were stage I (91%), and one was stage II (9%). Mean session attendance was 86.4 ± 9.5%. Mean intervention fidelity was 83.1 ± 13.1%. With regard to acceptability,  > 90% of participants positively rated all aspects of the intervention delivery. No adverse events related to exercise were recorded.ConclusionsThe hybrid delivery of a home-based resistance exercise program for individuals previously treated for early-stage NSCLC was found to be safe and feasible. Adaptations to the program for future interventions are required, particularly surrounding resistance exercise programming, and intervention delivery with home visits.Trial registrationClinicalTrials.gov: NCT05014035. Registered January 20, 2021.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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