Relationship between myopia control and amount of corneal refractive change after orthokeratology lens treatment

BMC Ophthalmology

Research

Lu Sun¹  Hong-Xin Song²  Zheng-Xuan Li²  Yun Chen³  Zhi-Qiang He³ 

[1] Beijing Aier-Intech Eye Hospital, 100021, Beijing, China;Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, National Engineering Research Center for Ophthalmology, #1 Dong Jiao Min Xiang, 100730, Beijing, China;Beijing Tongren Eye Center, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, National Engineering Research Center for Ophthalmology, #1 Dong Jiao Min Xiang, 100730, Beijing, China;Key Laboratory of Universal Wireless Communications, Ministry of Education, Beijing University of Posts and Telecommunications, No. 10 Xitucheng Road, 100876, Beijing, China;

关键词: Orthokeratology;    Corneal refractive change region;    Axial length;    Myopia control;   

DOI  :  10.1186/s12886-023-03178-8

 received in 2023-05-05, accepted in 2023-10-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundTo evaluate the relationship between amount of corneal refractive change (CRC) after wearing orthokeratology (Ortho-K) lenses and axial length (AL) growth.MethodsWe retrospectively enrolled 77 patients (77 eyes) aged 8–14 years who wore Ortho-K lenses more than 12 months. We divided the patients into 2 subgroups: spherical equivalent (SE) ≤ -3.0 D and SE > -3.0 D subgroup. The sagittal and tangential curvature maps and corneal topographic data within the 8-mm diameter ring at the baseline and during follow-up visits after wearing Ortho-K lens were recorded in addition to the area, height, and volume of the CRC region. The AL data were recorded at the baseline and during follow-up visits. Multivariate linear regression was conducted to analyze associations between the area, height, and volume of the CRC region, AL elongation, and SE.ResultsThe average change in the CRC region was 9.77 ± 0.60 D in height, 16.66 ± 3.61 mm2 in area, and 87.47 ± 8.96 D*mm2 in volume on the tangential diagram after wearing Ortho-K lenses for 3 months. The AL showed a change of 0.19 ± 0.14 mm after 1 year of Ortho-K lens wear (P < 0.05). At 1 year, AL elongation was negatively correlated with the area (P = 0.019) and volume (P < 0.001) of the CRC region. At 1 year, for every 1-mm2 increase in the area and every 1-D*mm2 increase in the volume of the CRC region, the average AL elongation decreased by 0.01 mm and 0.002 mm, respectively, in the multivariate analysis. In patients with SE ≤ -3.0 D, AL elongation was negatively correlated with the CRC-region volume (β = -0.002, P = 0.018), and in patients with SE > -3.0 D, AL elongation was negatively correlated with the CRC-region area (β = -0.017, P = 0.016).ConclusionsThe AL elongation-control efficacy of Ortho-K lenses may be related to the area and volume of the CRC region.

【 授权许可】

CC BY   
© The Author(s) 2023

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