Even low level of physical activity is associated with reduced mortality among people with metabolic syndrome, a population based study (the HUNT 2 study, Norway)

BMC Medicine

Research Article

Stig A Slørdahl¹  Tom IL Nilsen²  Dorthe Stensvold³  Javaid Nauman³  Ulrik Wisløff³  Lars Vatten⁴ 

[1]Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway

[2]St. Olavs Hospital, Postboks 3250 Sluppen, 7006, Trondheim, Norway

[3]Human Movement Science Programme, Norwegian University of Science and Technology, Loholt allé 81, Dragvoll, Trondheim, Norway

[4]K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway

[5]Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway

[6]St. Olavs Hospital, Postboks 3250 Sluppen, 7006, Trondheim, Norway

[7]K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway

[8]St. Olavs Hospital, Postboks 3250 Sluppen, 7006, Trondheim, Norway

[9]Department of Public Health, Norwegian University of Science and Technology, Postboks 8905, MTFS, 7491, Trondheim, Norway

关键词: metabolic syndrome;    physical activity;    mortality;   

DOI  :  10.1186/1741-7015-9-109

 received in 2011-07-06, accepted in 2011-09-29,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundLow levels of physical activity may increase the risk of developing metabolic syndrome, a cluster of metabolic factors that are associated with the risk of premature death. It has been suggested that physical activity may reduce the impact of factors associated with metabolic syndrome, but it is not known whether physical activity may reduce mortality in people with metabolic syndrome.MethodsIn a prospective study of 50,339 people, 13,449 had metabolic syndrome at baseline and were followed up for ten years to assess cause-specific mortality. The population was divided into two age groups: those younger than 65 years of age and those older than age 65. Information on their physical activity levels was collected at baseline.ResultsMetabolic syndrome was associated with higher mortality from all causes (hazard ratio (HR) 1.35, 95% confidence interval (95% CI) 1.20 to 1.52) and from cardiovascular causes (HR 1.78, 95% CI 1.39 to 2.29) in people younger than 65 years old than among other populations. In older people, there was no overall association of metabolic syndrome with mortality. People with metabolic syndrome who reported high levels of physical activity at baseline were at a reduced risk of death from all causes compared to those who reported no physical activity, both in the younger age group (HR 0.52, 95% CI 0.37 to 0.73) and in the older age group (HR 0.59, 95% CI 0.47 to 0.74).ConclusionAmong people with metabolic syndrome, physical activity was associated with reduced mortality from all causes and from cardiovascular causes. Compared to inactivity, even low levels of physical activity were associated with reduced mortality.

【 授权许可】

CC BY   
© Stensvold et al; licensee BioMed Central Ltd. 2011