Fulani show decreased susceptibility to Plasmodium falciparum infection versus Mossi: data from a community-wide screening and treatment of asymptomatic carriers in Burkina Faso

Malaria Journal

Commentary

Alfred B Tiono¹  Sodiomon B Sirima¹  Kamal Hamed² 

[1] Centre National de Recherche et de Formation sur le Paludisme, Ministère de la Santé, 01 BP 2208, Ouagadougou, Burkina Faso;Novartis Pharmaceuticals Corporation, One Health Plaza, East Hanover, 07936-1080, NJ, USA;

关键词: Malaria;    Plasmodium falciparum;    Mossi;    Fulani;    Artemether-lumefantrine;   

DOI  :  10.1186/1475-2875-12-163

 received in 2013-01-23, accepted in 2013-05-14,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundThe Fulani ethnic group is known to have a lower susceptibility to Plasmodium falciparum infection than the Mossi.MethodsThis commentary describes data from a recent cluster-randomized trial of community-wide screening and treatment of asymptomatic carriers of P. falciparum in 18 villages in Saponé, Burkina Faso.ResultsThe Fulani groups had a lower proportion of asymptomatic carriers at any occasion, a lower density of asexual forms and gametocytes of P. falciparum at baseline, and, in children under five years of age, lower rates of symptomatic malaria episodes per person-year than the Mossi.Discussion and conclusionThese data confirm previously reported differences in P. falciparum susceptibility between Fulani and Mossi.

【 授权许可】

CC BY   
© Tiono et al.; licensee BioMed Central Ltd. 2013