A nationwide population-based study of the inflammatory bowel diseases between 1998 and 2008 in Taiwan

BMC Gastroenterology

Research Article

Jau-Min Wong¹  Shu-Chen Wei¹  Cheng-Yi Wang¹  Chien-Chih Tung²  Meng-Tzu Weng³  Jen-Shin Kuo⁴  Ming-Jium Shieh⁵  Wen-Chao Ho⁶  Meng-Hung Lin⁶  Pau-Chung Chen⁷ 

[1] Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan;Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan;Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan;Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan;Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei, Taiwan;Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, 7 Chung Shan South Road, Taipei, Taiwan;Department of Internal Medicine, Kang-Ning General Hospital, Taipei, Taiwan;Department of Oncology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan;Department of Public Health, College of Public Health, China Medical University, Taichung, Taiwan;Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, 17 XuZhou Road, Taipei, Taiwan;Department of Public Health, National Taiwan University College of Public Health, Taipei, Taiwan;Department of Environmental and Occupational Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan;

关键词: Crohn’s disease;    Ulcerative colitis;    Incidence;    Prevalence;    Taiwan;    Nationwide;   

DOI  :  10.1186/1471-230X-13-166

 received in 2013-08-01, accepted in 2013-11-28,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundThe incidence of the inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), has been increasing in Asia. We probed the nationwide registered database to assess the incidence, prevalence, gender distribution, age of diagnosis and the survival status of IBD patients in Taiwan.MethodsA retrospective study was conducted to analyze the registered database compiled by the National Health Insurance provided by the Department of Health, Taiwan, from January 1998 through December 2008.ResultsA total of 1591 IBD patients were registered from 1998 to 2008 in Taiwan (CD: 385; UC: 1206). The incidence of CD increased from 0.19/100,000 in 1998 to 0.24/100,000 in 2008. The incidence of UC increased from 0.61/100,000 in 1998 to 0.94/100,000 in 2008. The prevalence of CD increased from 0.19/100,000 in 1998 to 1.78/100,000 in 2008. The prevalence of UC increased from 0.61/100,000 in 1998 to 7.62/100,000 in 2008. Male to female ratio for CD was 2.22 and 1.64 for UC. Age of registered for CD was predominantly between 20 to 39, and for UC between 30 to 49 years of age. The standardized mortality ratio (95% CI) was 4.97 (3.72–6.63) for CD and 1.78 (1.46–2.17) for UC, from 1998 to 2008 in Taiwan.ConclusionsUsing the Taiwan nationwide database for IBD, the incidence and prevalence of IBD in Taiwan significantly increased from 1998 to 2008. The mortality rate was higher for CD patients than UC patients, and both were higher than the general population.

【 授权许可】

Unknown   
© Wei et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.