期刊论文

【摘要】

The lipid phosphatidic acid (PA) has important roles in cell signaling and metabolic regulation in all organisms. New evidence indicates that PA also has an unprecedented role as a pH biosensor, coupling changes in pH to intracellular signaling pathways. pH sensing is a property of the phosphomonoester headgroup of PA. A number of other potent signaling lipids also contain headgroups with phosphomonoesters, implying that pH sensing by lipids may be widespread in biology.

【授权许可】

CC BY
© Shin and Loewen; licensee BioMed Central Ltd. 2011

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【参考文献】

[1]
[2]
[3]
[4]
[5]
[6]
[7]
[8]
[9]
[10]
[11]
[12]
[13]
[14]
[15]
[16]
[17]
[18]
[19]
[20]
[21]
[22]
[23]
[24]
[25]
[26]
[27]
[28]
[29]
[30]
[31]
[32]
[33]
[34]
[35]
[36]
[37]
[38]
[39]
[40]
[41]
[42]
[43]
[44]
[45]
[46]
[47]
[48]
[49]
[50]
[51]
[52]
[53]
[54]
[55]
[56]
[57]
[58]
[59]
[60]
[61]
[62]
[63]
[64]
[65]
[66]
[67]
[68]
[69]
[70]
[71]
[72]

BMC Biology
Putting the pH into phosphatidic acid signaling
Review
John JH Shin¹ Christopher JR Loewen¹
[1] Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, V6T 1Z3, Vancouver, BC, Canada;
关键词: Phosphatidic Acid; Phosphatidic Acid; Intracellular Membrane; Planar Cell Polarity; Anionic Lipid;
DOI : 10.1186/1741-7007-9-85
received in 2011-06-30, accepted in 2011-12-02, 发布年份 2011
来源: Springer
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