Relationships between cognitive function and body composition among community-dwelling older adults: a cross-sectional study

BMC Geriatrics

Research Article

Sohee Oh¹  Kyung-Soon Hong²  Ohk-Hyun Ryu³  Hong Ji Song⁴  Hye-Mi Noh⁴  Eun Young Lee⁴  Dong-Hyun Kim⁵  Jin-Young Jeong⁶ 

[1]Department of Biostatistics, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, South Korea

[2]Department of Cardiology, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, South Korea

[3]Department of Endocrinology, Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, South Korea

[4]Department of Family Medicine, Hallym University Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, South Korea

[5]Department of Social and Preventive Medicine, Hallym University College of Medicine, Chuncheon, South Korea

[6]Hallym Research Institute of Clinical Epidemiology, Hallym University, Chuncheon, South Korea

关键词: Body fat;    Cognition;    Dual-energy X-ray absorptiometry;    Obesity;    Older adult;   

DOI  :  10.1186/s12877-017-0651-9

 received in 2016-12-13, accepted in 2017-10-22,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundPrevious studies reported mixed results regarding the association between cognition and body weight in late life. We evaluated the relationships between cognitive function and body composition among community-dwelling older adults.MethodsThree hundred twenty subjects (≥65 years, women 53%) with available data of cognitive function and body composition from 2010 Hallym Aging Study. Cognitive function was assessed using Korean Mini-Mental State Examination (K-MMSE). Dual-energy X-ray absorptiometry (DEXA) was used for measuring body composition including body fat and lean body mass. Anthropometric measurements and laboratory data were collected in clinical examination. Body composition variables were divided into sex-specific tertiles, and examined by multivariable logistic regression.ResultsAmong female, the highest tertile group of fat mass and second tertile group of total lean body mass were associated with lower risk for cognitive impairment compared to the respective first tertile groups (odds ratios, 0.23 and 0.09, respectively; 95% confidence intervals, 0.04–0.88 and 0.01–0.44, respectively) after adjusting for confounding factors. In male, higher arm bone mineral content was associated with lower risk for cognitive impairment, but significance was lost after adjusting for adiponectin, age, and education.ConclusionsHigher fat mass and lean body mass were associated with lower risk of cognitive impairment in older women. These observations suggest that body fat and lean mass later in life might be beneficial for cognition.

【 授权许可】

CC BY   
© The Author(s). 2017