Oligodendroglioma of the ciliary body: a unique case report and the review of literature

BMC Cancer

Case Report

Shou ping Xu¹  Qi liang Guo²  Guo dong Cui³  Jie Hao⁴  Qian Yang⁵  Qing Guo⁶  Shou bin Sun⁷ 

[1] Department of General Surgery, the First Clinical Medical School of Harbin Medical University, Harbin, China;Department of Ophthalmology, Fourth Hospital of Harbin City, Heilongjiang Province, Harbin, China;Department of Ophthalmology, the Fifth Clinical Medical School of Harbin Medical University, Daqing, China;Department of Ophthalmology, the First Clinical Medical School of Harbin Medical University, Harbin, China;Department of life and engineering, Harbin Institute of Technology, Harbin, China;Department of life and engineering, Harbin Institute of Technology, Harbin, China;Department of Ophthalmology, the First Clinical Medical School of Harbin Medical University, Harbin, China;Optometry Clinic, the Forth Clinical Medical School of Harbin Medical University, Harbin, China;

关键词: Neural Stem Cell;    Malignant Glioma;    Retinal Detachment;    Retinitis Pigmentosa;    Oligodendroglioma;   

DOI  :  10.1186/1471-2407-10-579

 received in 2009-12-02, accepted in 2010-10-23,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundTo date, there is no report in the international literature of an oligodendroglioma of the ciliary body, nor is there an analysis of the possible origins of this lesion.Case presentationHere we report on a 52-year-old man admitted to our hospital with a ciliary body tumor revealed by clinical examination and ultrasound, computed tomography and magnetic resonance imaging studies. Following enucleation, pathological and immunohistochemical analyses were performed. Postoperative histopathological staining results included OLIGO-2(+) and GFAP(-), leading to a pathological diagnosis of oligodendroglioma of the ciliary body in the right eye (WHO grade II).ConclusionsSince malignant gliomas derive from transformed neural stem cells, the presence of oligodendroglioma in the ciliary body supports the hypothesis that gliomas can occur wherever neural stem cells exist. Tumors of the ciliary body derived from oligodendrocytes are difficult to diagnose; pathological analyses are essential.

【 授权许可】

CC BY   
© Guo et al; licensee BioMed Central Ltd. 2010