A population-based cross-sectional study of colorectal cancer screening practices of first-degree relatives of colorectal cancer patients

BMC Cancer

Research Article

Jody Simmons¹  Finlay A Macrae²  Robert W Sanson-Fisher³  Mariko L Carey³  Christine L Paul³  Ryan J Courtney⁴  David Hill⁵  Daniel Barker⁶  Catherine D’Este⁶ 

[1] Centre for Behavioural Research in Cancer, Cancer Council Victoria, Melbourne, Australia;Department of Colorectal Medicine and Genetics, The Royal Melbourne Hospital, Melbourne, Australia;Priority Research Centre for Health Behaviour, School of Medicine and Public Health, Faculty of Health, University of Newcastle, Callaghan, Australia;Hunter Medical Research Institute, University of Newcastle, Callaghan, Australia;Priority Research Centre for Health Behaviour, School of Medicine and Public Health, Faculty of Health, University of Newcastle, Callaghan, Australia;Hunter Medical Research Institute, University of Newcastle, Callaghan, Australia;Priority Research Centre for Health Behaviour, University of Newcastle, Room 269a, Level 2, David Maddison Building, 2308, Callaghan, Australia;Professorial Fellow, University of Melbourne, Melbourne, Australia;The Centre for Clinical Epidemiology and Biostatistics, Faculty of Health, University of Newcastle, Callaghan, Australia;

关键词: Colorectal cancer;    Screening;    Prevention;    Early detection;    Family history;   

DOI  :  10.1186/1471-2407-13-13

 received in 2012-08-15, accepted in 2012-12-27,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundThe aim of this study was to determine the proportions and predictors of first-degree relatives (FDRs) of colorectal cancer (CRC) patients (i) ever receiving any CRC testing and (ii) receiving CRC screening in accordance with CRC screening guidelines.MethodsColorectal cancer patients and their FDRs were recruited through the population-based Victorian Cancer Registry, Victoria, Australia. Seven hundred and seven FDRs completed telephone interviews. Of these, 405 FDRs were deemed asymptomatic and eligible for analysis.ResultsSixty-nine percent of FDRs had ever received any CRC testing. First-degree relatives of older age, those with private health insurance, siblings and FDRs who had ever been asked about family history of CRC by a doctor were significantly more likely than their counterparts to have ever received CRC testing. Twenty-five percent of FDRs “at or slightly above average risk” were adherent to CRC screening guidelines. For this group, adherence to guideline-recommended screening was significantly more likely to occur for male FDRs and those with a higher level of education. For persons at “moderately increased risk” and “potentially high risk”, 47% and 49% respectively adhered to CRC screening guidelines. For this group, guideline-recommended screening was significantly more likely to occur for FDRs who were living in metropolitan areas, siblings, those married or partnered and those ever asked about family history of CRC.ConclusionsA significant level of non-compliance with screening guidelines was evident among FDRs. Improved CRC screening in accordance with guidelines and effective systematic interventions to increase screening rates among population groups experiencing inequality are needed.Trial RegistrationAustralian and New Zealand Clinical Trial Registry: ACTRN12609000628246

【 授权许可】

CC BY   
© Courtney et al.; licensee BioMed Central Ltd. 2013